Description
With a place squarely in the spotlight for patients diagnosed with all manner of disease, APRNs must demonstrate not only support and compassion, but expertise to guide patients’ understanding of diagnoses and treatment plans.
This expertise goes beyond an understanding of disease and sciences, such as cellular pathophysiology. APRNs must become experts in their patients, understanding their medical backgrounds, pertinent characteristics, and other variables that can be factors in their diagnoses and treatments.
This week, you examine alterations in the immune system and the resultant disease processes. You consider patient characteristics, including racial and ethnic variables, and the impact they have on altered physiology.
Learning Objectives
Students will:
Evaluate cellular processes and alterations within cellular processes
Analyze alterations in the immune system that result in disease processes
Identify racial/ethnic variables that may impact physiological functioning
Evaluate the impact of patient characteristics on disorders and altered physiology
Assignment
Develop a 1- to 2-page case study analysis in which you:
Explain why you think the patient presented the symptoms described.
Identify the genes that may be associated with the development of the disease.
Explain the process of immunosuppression and the effect it has on body systems.
Scenario 2: A 30-year-old male presents to the clinic with a chief complaint of abdominal pain and cramping with mucus in his stool worsening over the last few weeks. He denies any fever but has had an increase in fatigue. He reports a weight loss of 10 pounds in the last month. His family history reveals his brother was diagnosed with Crohn’s disease. His labs reveal an elevated ESR, normal B12, and negative stool testing. He is sent for a plain abdominal x-ray which was normal.
Reminder: The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references. The sample paper provided at the Walden Writing Center provides an example of those required elements (available at https://academicguides.waldenu.edu/writingcenter/templatesLinks to an external site.). All papers submitted must use this formatting.
SUPPLEMENTARY RESOURCE- Note: These readings are intended to serve as supplementary to the Lecturio content provided in this course. Please refer/review these supplementary resources should you need help in reinforcing concepts and in preparation for completing this week’s Assessments.
McCance, K. L. & Huether, S. E. (2019). Pathophysiology: The biologic basis for disease in adults and children (8th ed.). St. Louis, MO: Mosby/Elsevier.
Chapter 7: Innate Immunity: Inflammation and Wound Healing
Chapter 8: Adaptive Immunity (stop at Generation of clonal diversity); Summary Review
Chapter 9: Alterations in Immunity and Inflammation (stop at Deficiencies in immunity); Summary Review
Chapter 10: Infection (stop at Infectious parasites and protozoans); (start at HIV); Summary Review
Chapter 11: Stress and Disease (stop at Stress, illness & coping); Summary Review
Chapter 12: Cancer Biology (stop at Resistance to destruction); Summary Review
Chapter 13: Cancer Epidemiology (stop at Environmental-Lifestyle factors); Summary Review
Justiz-Vaillant, A. A., & Zito, P. M. (2019). Immediate hypersensitivity reactions Download Immediate hypersensitivity reactions. In StatPearls. Treasure Island, FL: StatPearls Publishing. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK513315/Cred… Line: Immediate Hypersensitivity Reactions – StatPearls – NCBI Bookshelf. (2019, June 18). Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK513315/. Used with permission of Stat Pearls.
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3/5/24, 1:41 AM
Week 2: Assignment
Start Assignment
Due Sunday by 10:59pm
Points 100
Submitting a text entry box or a file upload
Attempts 0
Allowed Attempts 2
Back to Week at a Glance
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CASE STUDY ANALYSIS
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An understanding of cells and cell behavior is a critically important component of disease diagnosis and
treatment. But some diseases can be complex in nature, with a variety of factors and circumstances
impacting their emergence and severity.
Effective disease analysis often requires an understanding that goes beyond isolated cell behavior.
Genes, the environments in which cell processes operate, the impact of patient characteristics, and racial
and ethnic variables all can have an important impact.
An understanding of the signals and symptoms of alterations in cellular processes is a critical step in the
diagnosis and treatment of many diseases. For APRNs, this understanding can also help educate
patients and guide them through their treatment plans.
In this Assignment, you examine a case study and analyze the symptoms presented. You identify cell,
gene, and/or process elements that may be factors in the diagnosis, and you explain the implications to
patient health.
RESOURCES
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Week 2: Assignment
Be sure to review the Learning Resources before completing this activity.
Click the weekly resources link to access the resources.
WEEKLY RESOURCES (https://waldenu.instructure.com/courses/109910/modules/items/3962000)
To prepare:
By Day 1 of this week, you will be assigned to a specific case study for this Case Study Assignment.
Please see the “Announcements” section of the classroom for your assignment from your Instructor.
The Assignment
Develop a 1- to 2-page case study analysis in which you:
Explain why you think the patient presented the symptoms described.
Identify the genes that may be associated with the development of the disease.
Explain the process of immunosuppression and the effect it has on body systems.
BY DAY 7 OF WEEK 2
Submit your Case Study Analysis Assignment by Day 7 of Week 2.
Reminder: The College of Nursing requires that all papers submitted include a title page,
introduction, summary, and references. The sample paper provided at the Walden Writing Center
provides an example of those required elements (available at
https://academicguides.waldenu.edu/writingcenter/templates
(https://academicguides.waldenu.edu/writingcenter/templates) ). All papers submitted must use this
formatting.
SUBMISSION INFORMATION
Before submitting your final assignment, you can check your draft for authenticity. To check your
draft, access the Turnitin Drafts from the Start Here area.
1. To submit your completed assignment, save your Assignment as
WK2Assgn2_LastName_Firstinitial
2. Then, click on Start Assignment near the top of the page.
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Week 2: Assignment
3. Next, click on Upload File and select Submit Assignment for review.
NURS_6501_Week 2_Case Study_Assignment_Rubric
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Week 2: Assignment
Criteria
Develop a 1- to 2page case study
analysis, examining
the patient
symptoms
presented in the
case study. Be sure
to address the
following:Explain
why you think the
patient presented
the symptoms
described.
Ratings
Pts
30 to >27.0 pts
Excellent
27 to >24.0 pts
Good
24 to >22.0 pts
Fair
22 to >0 pts
Poor
The response
accurately and
The response
describes the
The response
describes the patient
The response
describes the patient
thoroughly
describes the
patient symptoms.
patient
symptoms. … The
response
symptoms in a
manner that is vague
or inaccurate. … The
symptoms in a
manner that is vague
and inaccurate, or the
… The response
includes accurate,
includes accurate
reasons, with
response includes
reasons for the
description is missing.
… The response does
clear, and detailed
reasons, with
explanation for the
explanation for
the symptoms
supported by
symptoms, with
explanations that are
vague or based on
not include reasons
for the symptoms, or
the explanations are
symptoms
supported by
evidence and/or
evidence and/or
research, as
appropriate, to
inappropriate
evidence/research.
vague or based on
inappropriate or no
evidence/research.
research, as
appropriate, to
support the
explanation.
30 pts
support the
explanation.
Identify the genes
that may be
associated with the
development of the
disease.
25 to >22.0 pts
Excellent
22 to >19.0 pts
Good
19 to >17.0 pts
Fair
17 to >0 pts
Poor
The response
includes an accurate,
The response
includes an
The response
includes a vague or
The response
includes a vague
complete, detailed,
and specific analysis
of the genes that
accurate analysis of
the genes that may
be associated with
inaccurate analysis
of the genes that
may be associated
or inaccurate
analysis of the
genes that may
may be associated
with the development
the development of
the disease.
with the
development of the
be associated
with the
disease.
development of
the disease is
missing.
of the disease.
Explain the process
of
immunosuppression
and the effect it has
on body systems.
30 to >27.0 pts
Excellent
27 to >24.0 pts
Good
24 to >17.0 pts
Fair
17 to >0 pts
Poor
The response
includes an
The response
includes an
The response
includes a vague or
The response
includes a vague or
accurate, complete,
detailed, and
specific explanation
accurate
explanation of the
process of
inaccurate
explanation of the
process of
inaccurate
explanation of the
process of
of the process of
immunosuppression
immunosuppression
and the effect it has
immunosuppression
and the effect it has
immunosuppression
and the effect it has
and the effect it has
on body systems.
on body systems.
on body systems.
on body systems.
https://waldenu.instructure.com/courses/109910/assignments/1290072?module_item_id=3961995
25 pts
30 pts
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Week 2: Assignment
Criteria
Written Expression
and Formatting Paragraph
Development and
Organization:
Paragraphs make
clear points that
support welldeveloped ideas,
flow logically, and
demonstrate
continuity of ideas.
Sentences are
carefully focused—
neither long and
Ratings
Pts
5 to >4.0 pts
Excellent
4 to >3.0 pts
Good
3 to >2.0 pts
Fair
2 to >0 pts
Poor
Paragraphs and
sentences follow
Paragraphs and
sentences follow
Paragraphs and
sentences follow
Paragraphs and
sentences follow
writing standards for
flow, continuity, and
clarity. … A clear and
writing standards
for flow, continuity,
and clarity 80% of
writing standards
for flow, continuity,
and clarity 60%–
writing standards
for flow,
continuity, and
comprehensive
purpose statement,
the time. …
Purpose,
79% of the time. …
Purpose,
clarity < 60% of
the time. ... No
introduction, and
conclusion are
provided that
introduction, and
conclusion of the
assignment are
introduction, and
conclusion of the
assignment are
purpose
statement,
introduction, or
delineate all required
criteria.
stated, yet are brief
and not descriptive.
vague or off topic.
conclusion were
provided.
5 pts
rambling nor short
and lacking
substance. A clear
and comprehensive
purpose statement
and introduction are
provided that
delineate all
required criteria.
Written Expression
and Formatting English Writing
Standards: Correct
grammar,
mechanics, and
proper punctuation
5 to >4.0 pts
Excellent
4 to >3.0 pts
Good
3 to >2.0 pts
Fair
2 to >0 pts
Poor
Uses correct
grammar,
Contains a few (1
or 2) grammar,
Contains several
(3 or 4) grammar,
Contains many (≥ 5)
grammar, spelling, and
spelling, and
punctuation with
no errors.
spelling, and
punctuation
errors.
spelling, and
punctuation errors.
punctuation errors that
interfere with the
reader’s understanding.
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5 pts
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Week 2: Assignment
Criteria
Written Expression
and Formatting The paper follows
correct APA format
for title page,
headings, font,
spacing, margins,
Ratings
Pts
5 to >4.0 pts
Excellent
4 to >3.0 pts
Good
3 to >2.0 pts
Fair
2 to >0 pts
Poor
Uses correct APA
format with no
Contains a few (1 or
2) APA format
Contains several (3
or 4) APA format
Contains many (≥
5) APA format
errors.
errors.
errors.
errors.
5 pts
indentations, page
numbers, running
heads,
parenthetical/in-text
citations, and
reference list.
Total Points: 100
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