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Week 6 Assignment
Part I: Research Questions
For each research question below, list at least two key words you would use to begin a literature
search on the topic:

What is the lived experience of being a survivor of a suicide attempt?

Do weekly text messages improve patient compliance with a treatment regimen?

What is the decision-making process for a woman considering having an abortion?

Is the use of silk-like synthetic fabrics for the linens of postsurgical patients effective in
reducing the risk of pressure ulcers?

Do children raised on vegetarian diets have different growth patterns than other children?

What is the course of appetite loss among cancer patients undergoing chemotherapy?

What is the effect of alcohol skin preparation before insulin injection on the incidence of local
and systemic infection?

Are bottle-fed babies introduced to solid foods sooner than breastfed babies?
Part II: Research Reviews
Read the abstract, introduction, and the first subsection under “Methods” of the report by Chase
and colleagues (“The effectiveness of medication adherence interventions among patients with
coronary artery disease”) and then answer the following questions:
1. What type of research review did the investigators undertake?
2. Did the researchers begin with a problem statement? Summarize the problem in two or
three sentences.
3. Did the researchers provide a statement of purpose? If so, what was it? Did they state
research questions? If yes, what were they?
4. Which bibliographic databases did the researchers search?
5. What keywords were used in the search?
6. Did the reviewers use the ancestry approach in their search for studies?
7. Did the researchers restrict their search to English-language reports?
8. How many studies ultimately were included in the review?
9. Were the studies included in the review qualitative, quantitative, or both?
10. Did the researchers do an adequate job of explaining the problem and their purpose in
undertaking the review?
11. Did the researchers appear to do a thorough job in their search for relevant studies?
12. Certain studies that were initially retrieved were eliminated. Do you think the researchers
provided a sound rationale for their decisions?
HHS Public Access
Author manuscript
Author Manuscript
J Cardiovasc Nurs. Author manuscript; available in PMC 2017 July 01.
Published in final edited form as:
J Cardiovasc Nurs. 2016 ; 31(4): 357–366. doi:10.1097/JCN.0000000000000259.
The Effectiveness of Medication Adherence Interventions among
Patients with Coronary Artery Disease: A Meta-analysis
Jo-Ana D. Chase, PhD, APRN-BC [Assistant Professor],
S343 School of Nursing, University of Missouri, Columbia, MO 65211
Author Manuscript
Jennifer L. Bogener, BSN,
University of Missouri, School of Nursing, School of Health Professions, 100 E. Green Meadows
Rd. Ste. 10, Columbia, MO 65203
Todd M. Ruppar, PhD, RN [Assistant Professor], and
S423 School of Nursing, University of Missouri, Columbia, MO 65211
Vicki S. Conn, PhD, RN, FAAN [Potter-Brinton Professor and Associate Dean for Research]
S317 School of Nursing, University of Missouri, Columbia, MO 65211
Jo-Ana D. Chase: [email protected]; Jennifer L. Bogener: [email protected]; Todd M. Ruppar:
[email protected]; Vicki S. Conn: [email protected]
Abstract
Author Manuscript
Background—Despite the known benefits of medication therapy for secondary prevention of
coronary artery disease (CAD), many patients do not adhere to prescribed medication regimens.
Medication nonadherence is associated with poor health outcomes and higher health care cost.
Objective—The purpose of this meta-analysis was to determine the overall effectiveness of
interventions designed to improve medication adherence (MA) among adults with CAD.
Additionally, sample, study design, and intervention characteristics were explored as potential
moderators to intervention effectiveness.
Author Manuscript
Methods—Comprehensive search strategies facilitated identification of two-group, treatment
versus control design studies testing MA interventions among patients with CAD. Data were
independently extracted by two trained research specialists. Standardized mean difference effect
sizes were calculated for eligible primary studies, adjusted for bias, then synthesized under a
random effects model. Homogeneity of variance was explored using a conventional heterogeneity
statistic. Exploratory moderator analyses were conducted using meta-analytic analogues for
ANOVA and regression for dichotomous and continuous moderators, respectively.
Results—Twenty-four primary studies were included in this meta-analysis. The overall effect
size of MA interventions, calculated from 18,839 participants, was 0.229 (p
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