Immunology Question

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Write a research proposal about the Assessment of Molecular biomarkers in the pathogenesis of cervical cancer. Research Objectives1. To preliminary investigate the prevalence of HPV-Dependent and Independent of Cervical Cancer among different clinical centers Assignment instructions: You must use books, articles in Journals, or reviews from ISI/WOS ONLY, and must be between 2019-2023. Use Times New Roman, subheading 12 bold, main text 11, line space 1.5, and justify alignment Vancouver citation. Your proposal should be plagiarism-free

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Write a research proposal with the following title:
Assessment of Molecular biomarkers in the pathogenesis of cervical cancer.
Assignment instructions:
• You must use books, articles in Journals or review from ISI/WOS ONLY and must be between 2019-2023.
• Use time new roman, subheading 12 bold, main text 11, line space 1.5, and justify alignment Vancouver citation.
• Your proposal should be plagiarism-free
Aim of the Study
A significant challenge in the field of oncology, particularly in cervical cancer research, is
understanding the prevalence and distribution of HPV-dependent and HPV-independent cervical cancers.
By conducting a preliminary study, our aim is to ascertain the prevalence rates of these two distinct
categories of cervical cancer. This investigation is not merely about quantifying incidence but also about
understanding the distribution patterns of these cancer types within a specific population. By categorizing
cervical cancers into HPV-dependent and independent types, we seek to provide a foundational
understanding that could inform future research and potential treatment strategies.
Research Objectives
1. To preliminary investigate the prevalence of HPV-Dependent and Independent of Cervical Cancer
among different clinical centers
1
01.Background – Rationale: (Background Literature review of previous studies on thesubject; and
justification of the study by stating the problem and its importance)
02.Aim of the Study: (Aim of the Study or the goal you need to achieve)
03.Methods: (Describe the research methods that could best achieve the study objectives. Study
Area/Setting: (the area or setting where the study will be conducted. This descriptionshould cover
the details relevant to the study topic) Study Subjects: (Inclusion and exclusion criteria of the study
subjects)
04.Study Design: (mention the type of study design eg cross-sectional, case-control, etc..)Sample
Size: (mention the input criteria for sample size estimation.) Sampling Technique:that will be used
in order to obtain a representative sample for your target population.)
05.Data Collection methods
(Describe the instruments used for data collection (questionnaire, observation recording from,etc.),
and studied variables included in these instruments, as well as the methods used to test for the
validity and reliability of the instrument. Techniques used should be briefly described and referenced.
Study definitions [e.g., case definition] should be mentioned.
06.Data Management- Statistical (Describe the analysis plan, tests used for dataanalysis
and statistical package(s) used)
07.Ethical Considerations: Informed Consent: If needed, please attach Informed Consentand/or extra
documents. Translated forms are provided when needed.)
08.References: (List as referred to and numbered in the proposal.)
2
Write a research proposal with the following title:
Assessment of Molecular biomarkers in the pathogenesis of cervical cancer.
Assignment instructions:
• You must use books, articles in Journals or review from ISI/WOS ONLY and must be between 2019-2023.
• Use time new roman, subheading 12 bold, main text 11, line space 1.5, and justify alignment Vancouver citation.
• Your proposal should be plagiarism-free
Aim of the Study
A significant challenge in the field of oncology, particularly in cervical cancer research, is
understanding the prevalence and distribution of HPV-dependent and HPV-independent cervical cancers.
By conducting a preliminary study, our aim is to ascertain the prevalence rates of these two distinct
categories of cervical cancer. This investigation is not merely about quantifying incidence but also about
understanding the distribution patterns of these cancer types within a specific population. By categorizing
cervical cancers into HPV-dependent and independent types, we seek to provide a foundational
understanding that could inform future research and potential treatment strategies.
Research Objectives
1. To preliminary investigate the prevalence of HPV-Dependent and Independent of Cervical Cancer
among different clinical centers
Study Design
A retrospective study will be conducted at Alburg centers across Saudi Arabia during the period from
2021 to 2023.
Sample Size and Data Collection
All/specific # patient’s medical records that met the study inclusion criteria will be collected from Alborg
centers.
Patient data will be sorted in an excel sheet and organized for statistical analysis.
Data Analysis
statistical analysis using SPSS
1
01.Background – Rationale: (Background Literature review of previous studies on thesubject; and
justification of the study by stating the problem and its importance)
02.Aim of the Study: (Aim of the Study or the goal you need to achieve)
03.Methods: (Describe the research methods that could best achieve the study objectives. Study
Area/Setting: (the area or setting where the study will be conducted. This descriptionshould cover
the details relevant to the study topic) Study Subjects: (Inclusion and exclusion criteria of the study
subjects)
04.Study Design: (mention the type of study design eg cross-sectional, case-control, etc..)Sample
Size: (mention the input criteria for sample size estimation.) Sampling Technique:that will be used
in order to obtain a representative sample for your target population.)
05.Data Collection methods
(Describe the instruments used for data collection (questionnaire, observation recording from,etc.),
and studied variables included in these instruments, as well as the methods used to test for the
validity and reliability of the instrument. Techniques used should be briefly described and referenced.
Study definitions [e.g., case definition] should be mentioned.
06.Data Management- Statistical (Describe the analysis plan, tests used for data
analysis and statistical package(s) used)
07.Ethical Considerations: Informed Consent: If needed, please attach Informed Consentand/or extra
documents. Translated forms are provided when needed.)
08.References: (List as referred to and numbered in the proposal.)
2

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