Description
hello i needa google slide presentation.
NOTE:
Please avoid using complex words and phrases. Use simple and easy-to-understand language.
Use bullet points instead of complete sentences.
Provide a complete explanation in simple words under each slide.
Example: Do not follow the example provided. Use bullet points instead of complete sentences.
one slide for each, the first page that has name and last page for references doesn’t count
here was the explanation of the disease, and i supposed to identify the name of the disease:
“senario:14=A 52 year old male entered your clinic complaining of nausea, diarrhea, vomiting, fatigue and fever symptoms that had started about 2 weeks earlier, shortly after he returned from a hunting trip. Although the fever and nausea had decreased, he still was experiencing diarrhea, headaches, aching joints and muscle pain. He noted that he and his 2 companions from the hunting trip had eaten some of the bear meat during the trip, and that one of his companions had been experiencing symptoms similar to his.”
Initial analysis of disease scenario and explanation: Name: Trichinellosis and/or Trichinosi
here is my explanation: Based on the symptoms and his history of eating bear meat, it’s likely that the 52-year-old man has Trichinosis, also known as trichinellosis. This illness comes from eating meat, like a bear, that hasn’t been cooked enough and contains tiny worms called Trichinella. His symptoms, like feeling sick, having diarrhea, vomiting, feeling tired, fever, headaches, and muscle pain, all match with what’s expected with Trichinosis. Even though it’s often linked with eating undercooked pork, other meats like bear, wild boar, or walrus can also carry this parasite. Doctors diagnose Trichinosis by looking at the symptoms, asking about what kind of meat was eaten, and doing tests to check for the worms. Once diagnosed, treatment involves taking medicine to help feel better and to get rid of the worms from the body. People need to cook meat properly to avoid getting sick like this. Ensuring meat is cooked all the way through helps kill any harmful parasites or bacteria hiding inside. Therefore, the man’s illness, Trichinosis, likely came from eating bear meat that wasn’t cooked enough. His symptoms match up with what’s expected for this illness. To treat it, he’ll need medication to feel better and get rid of the worms. It reminds everyone to cook their meat thoroughly to avoid getting sick from parasites or bacteri.
so therefore, I need you to make a google slide one slide for each part with pictures that has the:
disease name (including correct pronunciation…if you don’t know, look it up!), and analysis of the scenario (how/why did you decide that this was the disease?)
etiologic agent (including correct pronunciation of the name of the agent), and its general characteristics
key tests for isolation and identification of this organism (be specific for this microbe!); how would you isolate and identify this organism in the laboratory? Also, what specific tests would you have to do on a person to determine that this person has this disease?
means of transmission and usual disease reservoirs
historical information to include when and who isolated the microbe and any significance of its name
signs and symptoms of the disease; body system(s) usually affected
microbial virulence mechanisms contributing to the disease process
control & treatment for the disease
prevention, including current research about a vaccine or other means of control/prevention
Current local and global outbreaks (with incidence); what is the incidence of this disease in San Diego county/southern California, the US, and globally; this will take you some research online to find this information. You need to create a broad picture of where this disease is typically found.
minimum five reliable Internet references, plus any other references used. Wikipedia is NOT an acceptable reference. Sources of photos used in the presentation should be documented in the reference list. ________________________________________________________________________________________
Unformatted Attachment Preview
Disease of the Day
Scoring Sheet
NAME:_________________________________________
SCENARIO ________________________________________
Initial analysis of disease scenario and explanation
(handed in to instructor prior to oral presentation
10 points
Disease name/analysis of scenario (PPT)
4 points
Etiologic Agent
2 points
Characteristics of Etiologic Agent (specific)
5 points
Disease Reservoirs
3 points
Mode of Transmission
3 points
Key Tests for identification of the organism and disease
(be specific)
5 points
Signs and symptoms of disease/human systems affected
3 points
Historical information
4 points
Virulence factors
2 points
Control/ Treatment
4 points
Prevention/ Vaccine info, new clinical trials?
5 points
Current outbreaks/ cases locally (San Diego Cty), (U.S.)
and globally ( all with incidence)
5 points
General presentation quality (spelling, appropriate use of
scientific terms/words, etc)
10 points
References: properly done and must work. Must have 5,
so -2 points for each one missing or not working. If
reference not complete (not all 5 parts), -1 for each
10 points
DISEASE OF THE DAY
PARAMEDICAL MICROBIOLOGY
PROJECT #1: 75 Points Maximum
This is the first of two projects that you will do this semester. You will be randomly assigned a
scenario for a disease and a date on which you will make a presentation to the class.
The first thing to do is to evaluate the scenario and determine what you think the disease is in
your scenario. You will most likely have to do some research on a variety of diseases in order to
accomplish this. Once you think you know what your disease is, you should give the instructor a
single page typewritten (double spaced) analysis of why you believe that is the disease. You
should clearly lay out your supporting evidence in this analysis. If your analysis is correct, the
instructor will let you know, and you may proceed with the remainder of the project. If your
answer is incorrect, the instructor will return the report to you, and you will have to continue to
research the project. Do not leave this part of the project to the last minute! It should be
turned in to the instructor as soon as possible. This part of the project will be worth a
maximum of 10 points.
Once you have correctly identified the disease, you may proceed with the remainder of the
project. You will have a maximum of 10 minutes to present the following information in a
PowerPoint presentation. This part of the project will be worth a maximum of 65 points:
•
•
•
•
•
•
•
•
•
•
•
disease name (including correct pronunciation…if you don’t know, look it up!), and
analysis of the scenario (how/why did you decide that this was the disease?)
etiologic agent (including correct pronunciation of the name of the agent), and its
general characteristics
key tests for isolation and identification of this organism (be specific for this microbe!);
how would you isolate and identify this organism in the laboratory? Also, what specific
tests would you have to do on a person to determine that this person has this disease?
means of transmission and usual disease reservoirs
historical information to include when and who isolated the microbe and any significance
of its name
signs and symptoms of the disease; body system(s) usually affected
microbial virulence mechanisms contributing to the disease process
control & treatment for the disease
prevention, including current research about a vaccine or other means of
control/prevention
Current local and global outbreaks (with incidence); what is the incidence of this disease
in San Diego county/southern California, the US, and globally; this will take you some
research online to find this information. You need to create a broad picture of where this
disease is typically found.
minimum five reliable Internet references, plus any other references used. Wikipedia is
NOT an acceptable reference. Sources of photos used in the presentation should be
documented in the reference list.
Initial analysis of disease scenario and explanation
(handed in to instructor prior to oral presentation
10 points
Disease name/analysis of scenario (Power point)
4 points
Etiologic agent
2 points
Characteristics of etiologic agent (specific)
5 points
Disease Reservoirs
3 points
Mode of Transmission
3 points
Key Tests for identification of the organism & the disease
5 points
(be specific)
Signs/ symptoms of disease /human systems affected
3 points
Historical information
4 points
Virulence factors
2 points
Control/ Treatment
4 points
Prevention/ Vaccine info, new clinical trials?
5 points
Current outbreaks/ cases locally (San Diego Cty), (U.S.)
and globally ( all with incidence)
5 points
General presentation quality (spelling, appropriate use of
scientific terms/words, etc)
10 points
References: properly done and must work. Must have 5,
so -2 points for each one missing or not working. If
reference not complete (not all 5 parts), -1 for each
10 points
TOTAL
75 points
When selecting online references, remember that not all information on the WWW is reliable.
Wikipedia is not a reliable source and will not be counted as an acceptable reference.
Always try to use journal articles or governmental documents as the “authority,” and not rely on
commercial sites (.com) unless the same information appears in multiple references one of
which can be tracked back to an authentic reference. Two references with the same URL except
for the last part will be considered the same reference, like different pages in a book. Include all
sources used; reference books and periodicals by a standard format.
Be VERY careful when referencing online sites. Each underscore, period, or capital letter must
be exact, or we will not be able to find the site. Always check your references before reporting
them by using the OPEN feature on your browser. If your reference will not open, it will not be
counted toward your grade.
To report your sources, prepare a bibliography on the last slide of your PowerPoint presentation
and number all references used. Then in the body of your report, give the number of the
reference you used for information. This is called end notes, which you have probably used for
other research papers. As with any report, be sure to paraphrase the information you use. If you
choose to use direct quotes from the article, you must use quotation marks. I will be checking
the references, so be sure NOT to plagiarize!!
There are five required parts of an Internet reference in order to receive full credit:
•
•
•
•
•
the author of the article, if available.
title of the article
the date written/updated
Internet address (URL). For example,
http://www2.austin.cc.tx.us/microbio/2704/syllabus.html is the URL or reference for this
page, which should show in your browser heading. An easy way to get this reference is
to copy it from your browser and paste into your word processing program, so typos will
not be made.
the date you visited the site.
Guidelines for PowerPoint Presentation
Your presentation is an important means of exchanging information with your fellow students.
They (and you) will be learning information from these presentations that they will be tested on
at the end of the semester. Therefore, it is important that you do an effective presentation.
All presentations must be done in Power Point and must be brought to class on a standard flash
drive that fits a USB port. If you do your presentation on a Mac at home, make sure you
test it out on a PC before you bring it to class. We have occasionally had compatibility
problems for people using Macs, especially if the software is older!
The total time allowed for the talk is 15 minutes, including questions. Therefore, you should plan
your talk for 10 minutes, and allow the last 5 minutes for questions. It is usually a good idea to
plan for about 1 minute per slide in the presentation (you may use your bibliography slide at the
end as an extra slide, as you will not actually talk about that slide in class). You should also
have a title slide. That means a total of approximately 12 slides.
Make an outline of the information you need to present, decide how many slides you need for
each point you need to make.
Do not write in complete sentences; use short phrases on the slides as a memory jogger of the
points you need to make.
PRACTICE, PRACTICE, PRACTICE! Due to the time constraints, it is very important that you
practice delivering your presentation and time it to see how long it takes. Adjust the content
accordingly during practice to fill the allotted time.
Be prepared! Do not talk about a topic unless you have a slide to go with it. Do talk about every
slide you show. There is an ideal balance between too little and too much on a slide. The slides
should require some explanation in order to hold the interest of the audience.
Use fonts that will be large enough to read; never use a font smaller than 12 point.
The following pages list some useful links to websites. They are not the only sites that
are available; there are many more. These will just be there to get you started.
All the Virology on the WWW
http://www.virology.net
Centers for Disease Control and Prevention Home Page
http://www.cdc.gov/
Gateway to Government Food Safety Information
http://www.foodsafety.gov/
Hardin MD: Infectious Diseases and Microbiology
http://www.lib.uiowa.edu/hardin/md/micro.html
Health Canada: Home Page
http://www.hc-sc.gc.ca/index_e.html
Medline Plus Health Information
http://www.nlm.nih.gov/medlineplus/infectiousdiseases.html
National Center for Infectious Diseases
https://www.cdc.gov/ddid/centers.html
National Institute of Allergy and Infectious Diseases
http://www.niaid.nih.gov/
New York State Communicable Diseases
http://www.health.state.ny.us/nysdoh/communicable_diseases/en/index.htm
World Health Organization WWW Home Page
http://www.who.ch/
Public Health Image Library
http://phil.cdc.gov/phil/home.asp
A recent immigrant from Brazil comes to the
clinic with lesions on the skin of his feet and
ankles. The lesions are few, but large and
well-defined, pale inside, and red and
inflamed around the edges. They do not hurt.
The man complains of numbness in his feet
and toes.
Martha A. Wild
Leprosy is now usually called Hansen’s disease
◦ stigma attached to the original term.
Diagnosis based on clinical manifestations
◦ Appearance of hypo-pigmented lesions
◦ Lesions painless
◦ Numbness of extremities
◦ Country of origin –
Brazil has a very high incidence of Hansen’s disease
Positive biopsies should be obtained to confirm
◦ Acid fast bacilli on biopsy material
Mycobacterium leprae
◦ (mī-kō-bak-TI-rē-um LEP-rē)
Intracellular acid-fast, gram
positive bacillus
Obligate, intracellular
parasite
Infects Schwann cells
◦ Peripheral nerves
Can not be cultured in
artificial media
Can be grown in mouse foot
pads and in armadillos
Source:
CDC
Two forms of disease
Characteristic skin lesions
Causes peripheral neurological damage
◦ Tuberculoid (Paucibacillary): milder disease, characterized
by one or more hypopigmented skin macules
◦ Multibacillary: symmetric skin lesions, nodules, plaques,
thickened dermis and involvement of nasal mucosa
◦ Pale inside (hypopigmented), Inflamed borders, numbness
◦ Preference for growth in outer, cooler parts of human body
◦ Particularly in hands and feet
◦ Ultimately causes sensory loss
Temperature first sensation lost; then light touch, then pain then deep
pressure
◦ Numbness may occur before skin lesions appear
Mainly affects skin and nerves of
peripheral nervous system
The debilitating effects of untreated
Hansen’s disease are not due solely to
the bacteria, but to the loss of sensation.
Without sensation, extremities are often
injured and become infected, resulting in
loss of fingers, toes, hands, etc.
Early treatment prevents long term
debilitating effects
Presence of an anesthetic (numb) skin
patch
Positive skin smear
◦ Inside of a fine cut within a lesion is scraped
with a scalpel and spread on a slide
◦ Slide is heat dried and stained by the ZiehlNeelsen method
◦ Red colored acid fast bacilli are seen
Thickened peripheral nerve(s)
◦ Nerve biopsies performed
Positive skin smear
Humans are the primary reservoirs for the
disease
Armadillos, chimpanzees & mangabey
monkeys may serve as reservoirs
Not highly infectious; Most people are immune to leprosy;
susceptibility may be at least partly inherited
Mode of transmission unclear
◦ Most current ideas indicate infection through lining of nose or
broken skin from droplets from nose and mouth
M. leprae reproduces very slowly, incubation period is about
5 years and symptoms may take as long as 20 years to
appear
◦ Makes it difficult to determine source of original infection
Occurs in all races and both sexes
Rare in infants, children are most susceptible, bimodal age
distribution peaks at 10-14 years and 35-44 years
Obligate intracellular parasite
◦ Hidden from immune system
M. leprae specific glycolipid involved in
invasion of Schwann cells
◦ Good candidate for vaccine or drug therapy
◦ Recent use for new diagnostic
Damage to body is done by the body’s strong
reaction to the antigens of the dead bacilli
Some races & ethnic groups are more susceptible,
possibly due to natural immunity within some
populations
Hansen’s disease has been recognized as a
communicable disease for thousands of
years
◦ India (600BC), Far East, Europe
Often confused with ringworm and other
afflictions in previous centuries
Patients isolated from contact with others in
leper colonies
1873 Gerhard Hansen, a Norwegian,
discovered that a bacterium causes leprosy.
◦ First bacillus associated with human disease.
Since the exact way the disease is transmitted is
unknown, prevention is not absolute
◦ Best way to prevent spread is early diagnosis and treatment
of people who are infected
◦ Carefully wash or dispose of handkerchiefs or other items
soiled with secretions from the nose and respiratory tract of
patients with Hansen’s disease
◦ For household contacts, immediate and annual examination
for at least 5 years after contact with a person who is
infectious is recommended
Historically, 500-600,000 new cases/year
globally
◦ Incidence has been dropping significantly (20%/year)
2005 less than 300,000 new cases world wide (WHO data)
◦ Most cases found in tropical countries
Brazil, Madagascar, Nepal, Mozambique, Tanzania (90% of cases)
◦ Only 100-200 new cases per year in the U.S.
In 2005, 166 cases were reported in the U.S.
24 of the cases were in California
Until 1940s, treatment was with injections of
oil from the chaulmoogra nut.
1941: Promin, a sulfone drug (side effects)
1950s: Dapsone (resistance developed)
1970s-present: Multidrug therapy
◦ dapsone, rifampicin, and clofazimine
◦ 6 month to 2 year course of treatment
◦ thalidomide for certain indications
No vaccine available
◦ Inability to culture is a problem
◦ Work is being done to find an effective vaccine
Susceptibility to leprosy. www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=246300.
Visited 3/20/09
www.aifo.it/english/resources/online/courses/ssmear/smear15.htm Skin smears.
Visited 2/25/09
Biological Characteristics: Infectious Agent.
www.stanford.edu/class/humbio103/ParaSites2005/Leprosy/bio.htm Visited
2/30/09
www.cdc.gov/ncidod/dbmd/diseaseinfo/hansens_t.htm Visited 3/15/09
genomebiology.com/2001/2/8/reviews/1023 Visited 3/15/09
Vanderborght PR, Pacheco AG, Moraes ME, Antoni G, Romero M, Verville A, Thai
VH, Huong NT, Ba NN, Schurr E, Sarno EN, Moraes MO. HLA-DRB1*04 and DRB1*10
are associated with resistance and susceptibility, respectively, in Brazilian and
Vietnamese leprosy patients. Genes Immun. 2007 Jun;8(4):320-4. Epub 2007 Mar
29.
Wieles B, Ottenhoff TH, Steenwijk TM, Franken KL, de Vries RR, Langermans JA.
Increased intracellular survival of Mycobacterium smegmatis containing the
Mycobacterium leprae thioredoxin-thioredoxin reductase gene. Infect Immun.
1997 Jul;65(7):2537-41.
Disease of the Day
Scoring Sheet
NAME:_________________________________________
SCENARIO ________________________________________
Initial analysis of disease scenario and explanation
(handed in to instructor prior to oral presentation
10 points
Disease name/analysis of scenario (PPT)
4 points
Etiologic Agent
2 points
Characteristics of Etiologic Agent (specific)
5 points
Disease Reservoirs
3 points
Mode of Transmission
3 points
Key Tests for identification of the organism and disease
(be specific)
5 points
Signs and symptoms of disease/human systems affected
3 points
Historical information
4 points
Virulence factors
2 points
Control/ Treatment
4 points
Prevention/ Vaccine info, new clinical trials?
5 points
Current outbreaks/ cases locally (San Diego Cty), (U.S.)
and globally ( all with incidence)
5 points
General presentation quality (spelling, appropriate use of
scientific terms/words, etc)
10 points
References: properly done and must work. Must have 5,
so -2 points for each one missing or not working. If
reference not complete (not all 5 parts), -1 for each
10 points
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